New Course
Want to learn about Toxicology & Human Health Risk Assessment in a live streaming virtual classroom?
Broken down into three separate 2-hour sessions which are run over three separate days, this live streaming class provides a thorough introduction to toxicology & human health risk assessment.
It is ideal for anyone who wishes to avoid the current problems and cost of travelling but wants something more substantial than a webinar or eLearning course.
The material is presented in such a way that the underlying principles are perfect for anyone who is involved in workplace risk assessments (e.g.) COSHH, or desk-based risk assessments (e.g. registration work for chemical control regulations), etc.
In order to ensure maximum involvement in the course, there will be only a limited number of places as all delegates are encouraged, where possible, to use a headset with microphone to enable them to talk to the rest of the group and ask/answer questions.
SESSION 1 – Introduction to Toxicology, terminology and dose-response (2 hours)
Chemicals, and homeostasis
- What is toxicology and how it differs to ecotoxicology
- Chemicals are all around us
- Cells, tissues, organs, organ systems,
- Homeostasis
- Adaptation and cell injury
- Cellular responses to injury
- Acute and chronic toxicity
- Adverse effects
The dose makes the poison
- Dose-response curves
- Thresholded and non-thresholded effects
- NOAEL and LOAEL
Introduction to how chemicals cause harm
- Local and systemic effects
Basic Toxicokinetics
- Absorption, distribution, metabolism and excretion.
- How knowledge of toxicokinetics can help in understanding species differences in response to chemical exposure.
SESSION 2 – How chemicals cause harm & assessment of toxicity (2 hours)
How chemicals cause harm (I) – local effects
Irritation and corrosion (skin, eyes and respiratory tract)
How chemicals cause harm (II) – Systemic effects
- Target organ toxicity (with specific reference to the liver and kidneys)
- Reproductive and developmental effects
- Carcinogenicity
- Genetic toxicology
- Skin and respiratory sensitisers.
Assessment of Toxicity (I) – Introduction
- Where to find data and how to evaluate it
- Alternative methods and the 3Rs
- Common terminology, in vitro, ex vivo, in vivo, in silico, in chemico
- The basic design of toxicity studies (control, replicates, etc)
Assessment of Toxicity (II) – Methods
- Acute toxicity
- Repeated dose toxicity
- Genetic toxicology
- Carcinogenicity studies
SESSION 3 – Assessment of Toxicity (III) and introduction to Human Health Risk Assessment (2 hours)
- Reproductive and developmental toxicity studies
- Sensitisation studies (skin and respiratory)
- Irritation and corrosion
- Limitations of toxicity testing
Introduction to human health risk assessment
- Prospective and retrospective risk assessment
- Hazard, exposure and the relationship to risk
- Hazard characterisation and risk characterisation
- Safety factors, uncertainty factors and assessment factors
- Exposure routes and exposure assessment
- Risk management measures
- Authors of safety data sheets (SDSs) throughout the supply chain
- Product stewards
- Regulatory affairs managers
- Health and safety professionals
- Occupational health professionals
- Product safety professionals
- Attendance on the live streaming 6-hour (split over three sessions) training class.
- All course materials (slides and course notes)
- A copy of the recording for your own personal use.
- A certificate of attendance for your training records.
Furthermore, you will be able to contact the trainer at any time both during and after completion of the course.
Laura holds an MSc in Applied Toxicology, a BSc (Hons) Chemistry, PgC Occupational Hygiene and PGCE Post Compulsory Teaching Qualification.
She has worked for many years in industry working in product stewardship which includes writing safety data sheets, classification and labelling, regulatory submissions and workplace risk assessments. She is an experienced trainer and a published author.
Her recent book ‘A Practical Guide to Toxicology and Human Health Risk Assessment (John Wiley & Sons, December 2018)
Testimonials
Unable to attend the scheduled date/time of webinar?
Please contact me if you are unable to attend a scheduled date/time of a webinar and we can schedule one-off dates/times to suit.
This is particularly useful if you are based on the west coast of the USA/Canada or Asia-Pacific region where the timings of the webinars might be inconvenient!
